Inhibitors | Comment | Organism | Structure |
---|---|---|---|
indomethacin | cytosolic enzyme | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Rattus norvegicus | 5737 | - |
microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
trans-1,2-dihydrobenzene-1,2-diol + NAD(P)+ | Rattus norvegicus | - |
catechol + NAD(P)H | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
microsomes: dihydrodiol dehydrogenase and 3alpha-hydroxysteroid dehydrogenase are different enzymes, cytosol: dihydrodiol dehydrogenase and 3alpha-hydroxysteroid dehydrogenase activity is unseparable | - |
Purification (Comment) | Organism |
---|---|
purified from microsomes | Rattus norvegicus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
trans-1,2-dihydrobenzene-1,2-diol + NADP+ = catechol + NADPH + H+ | the cytosolic, but not the microsomal, enzyme is identical with 3alpha-hydroxysteroid dehydrogenase EC 1.1.1.50 | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.62 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-acenaphthenol + NAD(P)+ | - |
Rattus norvegicus | ? | - |
? | |
trans-1,2-dihydrobenzene-1,2-diol + NAD(P)+ | - |
Rattus norvegicus | catechol + NAD(P)H | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Rattus norvegicus |