Inhibitors | Comment | Organism | Structure |
---|---|---|---|
8-isoprenyl-5'-geranyl-5,7,2',4'-tetrahydroxy flavanone | competitive inhibitor | Agaricus bisporus | |
albafuran A | - |
Agaricus bisporus | |
kojic acid | - |
Agaricus bisporus | |
kuwanon A | - |
Agaricus bisporus | |
kuwanon E | competitive inhibitor | Agaricus bisporus | |
kuwanon U | - |
Agaricus bisporus | |
moracin M | competitive inhibitor | Agaricus bisporus | |
moracin N | competitive inhibitor | Agaricus bisporus | |
moracinoside M | competitive inhibitor | Agaricus bisporus | |
morusinol | - |
Agaricus bisporus | |
neocyclomorusin | competitive inhibitor | Agaricus bisporus | |
norartocarpetin | competitive inhibitor | Agaricus bisporus | |
steppogenin | competitive inhibitor | Agaricus bisporus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-DOPA + O2 | - |
Agaricus bisporus | dopaquinone + H2O | - |
? | |
L-tyrosine + O2 | - |
Agaricus bisporus | dopaquinone + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
polyphenoloxidase | - |
Agaricus bisporus |
PPO | - |
Agaricus bisporus |
tyrosinase | - |
Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0012 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | norartocarpetin | |
0.0013 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | steppogenin | |
0.0074 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | moracin M | |
0.0163 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kojic acid | |
0.0265 | - |
using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | steppogenin | |
0.0442 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | 8-isoprenyl-5'-geranyl-5,7,2',4'-tetrahydroxy flavanone | |
0.0475 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kuwanon E | |
0.0646 | - |
using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | moracin M | |
0.0825 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | moracinoside M | |
0.0985 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | albafuran A | |
0.1274 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | neocyclomorusin | |
0.1318 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kuwanon A | |
0.1603 | - |
using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | moracin N | |
0.2 | - |
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | norartocarpetin | |
0.2 | - |
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kuwanon A | |
0.2 | - |
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kuwanon E | |
0.2 | - |
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kuwanon U | |
0.2 | - |
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | 8-isoprenyl-5'-geranyl-5,7,2',4'-tetrahydroxy flavanone | |
0.2 | - |
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | morusinol | |
0.2 | - |
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | neocyclomorusin | |
0.2 | - |
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | moracin N | |
0.2 | - |
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | albafuran A | |
0.2 | - |
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | moracinoside M | |
0.2 | - |
IC50 above 0.2 mM, using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | kuwanon U | |
0.2 | - |
IC50 above 0.2 mM, using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C | Agaricus bisporus | morusinol |