Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,3,4'-trihydroxy-4-methoxydeoxybenzoin | displays stable and significant inhibitory effect on tyrosinase activity | Agaricus bisporus | |
2,3,4,4'-tetrahydroxydeoxybenzoin | - |
Agaricus bisporus | |
2,3,4-trihydroxy-3',4'-dimethoxydeoxybenzoin | - |
Agaricus bisporus | |
2,3,4-trihydroxy-4'-methoxydeoxybenzoin | - |
Agaricus bisporus | |
2,4,4',6-tetrahydroxydeoxybenzoin | - |
Agaricus bisporus | |
2,4,4'-trihydroxydeoxybenzoin | - |
Agaricus bisporus | |
2,4,5-trihydroxy-4'-methoxydeoxybenzoin | - |
Agaricus bisporus | |
2,4,6-trihydroxy-4'-methoxydeoxybenzoin | - |
Agaricus bisporus | |
2,4-dihydroxy-3',4'-dimethoxydeoxybenzoin | - |
Agaricus bisporus | |
2,4-dihydroxy-4'-methoxydeoxybenzoin | - |
Agaricus bisporus | |
3,4-dihydroxy-4'-methoxydeoxybenzoin | - |
Agaricus bisporus | |
kojic acid | - |
Agaricus bisporus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tyrosine + L-dopa + O2 | - |
Agaricus bisporus | L-dopa + dopaquinone + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
tyrosinase | - |
Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0431 | - |
at incubation interval of 1.5 h | Agaricus bisporus | 2,3,4'-trihydroxy-4-methoxydeoxybenzoin | |
0.04337 | - |
at incubation interval of 0.5 h | Agaricus bisporus | 2,3,4'-trihydroxy-4-methoxydeoxybenzoin | |
0.0461 | - |
at incubation interval of 2.5 h | Agaricus bisporus | 2,3,4'-trihydroxy-4-methoxydeoxybenzoin | |
0.07105 | - |
at incubation interval of 0.5 h | Agaricus bisporus | 2,4,6-trihydroxy-4'-methoxydeoxybenzoin | |
0.0788 | - |
at incubation interval of 0.5 h | Agaricus bisporus | 2,4-dihydroxy-4'-methoxydeoxybenzoin | |
0.08435 | - |
at incubation interval of 0.5 h | Agaricus bisporus | 2,4,5-trihydroxy-4'-methoxydeoxybenzoin | |
0.1121 | - |
at incubation interval of 0.5 h | Agaricus bisporus | 2,4-dihydroxy-3',4'-dimethoxydeoxybenzoin | |
0.1328 | - |
at incubation interval of 0.5 h | Agaricus bisporus | kojic acid | |
0.1359 | - |
at incubation interval of 1.5 h | Agaricus bisporus | 2,4,4'-trihydroxydeoxybenzoin | |
0.1442 | - |
at incubation interval of 1.5 h | Agaricus bisporus | 2,4,5-trihydroxy-4'-methoxydeoxybenzoin | |
0.1604 | - |
at incubation interval of 1.5 h | Agaricus bisporus | 2,4-dihydroxy-4'-methoxydeoxybenzoin | |
0.168 | - |
at incubation interval of 1.5 h | Agaricus bisporus | 3,4-dihydroxy-4'-methoxydeoxybenzoin | |
0.1724 | - |
at incubation interval of 2.5 h | Agaricus bisporus | 2,4,4'-trihydroxydeoxybenzoin | |
0.1777 | - |
at incubation interval of 2.5 h | Agaricus bisporus | 3,4-dihydroxy-4'-methoxydeoxybenzoin | |
0.1785 | - |
at incubation interval of 0.5 h | Agaricus bisporus | 2,4,4'-trihydroxydeoxybenzoin | |
0.1814 | - |
at incubation interval of 2.5 h | Agaricus bisporus | 2,4-dihydroxy-4'-methoxydeoxybenzoin | |
0.1974 | - |
at incubation interval of 2.5 h | Agaricus bisporus | 2,4,5-trihydroxy-4'-methoxydeoxybenzoin | |
0.2033 | - |
at incubation interval of 1.5 h | Agaricus bisporus | 2,3,4-trihydroxy-4'-methoxydeoxybenzoin | |
0.2091 | - |
at incubation interval of 1.5 h | Agaricus bisporus | 2,4-dihydroxy-3',4'-dimethoxydeoxybenzoin | |
0.2119 | - |
at incubation interval of 2.5 h | Agaricus bisporus | 2,3,4-trihydroxy-4'-methoxydeoxybenzoin | |
0.2139 | - |
at incubation interval of 1.5 h | Agaricus bisporus | 2,4,6-trihydroxy-4'-methoxydeoxybenzoin | |
0.2251 | - |
at incubation interval of 1.5 h | Agaricus bisporus | kojic acid | |
0.2302 | - |
at incubation interval of 2.5 h | Agaricus bisporus | 2,4,6-trihydroxy-4'-methoxydeoxybenzoin | |
0.2397 | - |
at incubation interval of 2.5 h | Agaricus bisporus | 2,4-dihydroxy-3',4'-dimethoxydeoxybenzoin | |
0.2613 | - |
at incubation interval of 2.5 h | Agaricus bisporus | 2,4,4',6-tetrahydroxydeoxybenzoin | |
0.3 | - |
IC50 above 0.3 mM, at incubation interval of 0.5 h | Agaricus bisporus | 2,3,4,4'-tetrahydroxydeoxybenzoin | |
0.3 | - |
IC50 above 0.3 mM, at incubation interval of 0.5 h | Agaricus bisporus | 2,3,4-trihydroxy-4'-methoxydeoxybenzoin | |
0.3 | - |
IC50 above 0.3 mM, at incubation interval of 0.5 h | Agaricus bisporus | 3,4-dihydroxy-4'-methoxydeoxybenzoin | |
0.3 | - |
IC50 above 0.3 mM, at incubation interval of 0.5 h | Agaricus bisporus | 2,4,4',6-tetrahydroxydeoxybenzoin | |
0.3 | - |
IC50 above 0.3 mM, at incubation interval of 1.5 h | Agaricus bisporus | 2,3,4,4'-tetrahydroxydeoxybenzoin | |
0.3 | - |
IC50 above 0.3 mM, at incubation interval of 1.5 h | Agaricus bisporus | 2,4,4',6-tetrahydroxydeoxybenzoin | |
0.4383 | - |
at incubation interval of 2.5 h | Agaricus bisporus | kojic acid | |
0.5 | - |
IC50 above 0.5 mM, at incubation interval of 2.5 h | Agaricus bisporus | 2,3,4,4'-tetrahydroxydeoxybenzoin |