Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | 1.0 mM, 68% inhibition, reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin | Rattus norvegicus | |
2-(1-octadecylthio)ethanol | reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin | Rattus norvegicus | |
3-(1-octadecylthio)propan-1,2-diol | 0.5 mM, 64% inhibition, reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin | Rattus norvegicus | |
8-hydroxyquinoline | 1.0 mM, 15% inhibition, reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin; reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin | Rattus norvegicus | |
8-Hydroxyquinoline-5-sulfonic acid | 1.0 mM, 13% inhibition, reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin | Rattus norvegicus | |
CHAPS | 0.2% or 0.5%, activity is reduced by ca. 15% after 30 min | Rattus norvegicus | |
EDTA | 5 mM, 16% inhibition, reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin | Rattus norvegicus | |
hexadecan-1,2-diol | reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin | Rattus norvegicus | |
NEM | 8.0 mM; 91% inhibition, reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin | Rattus norvegicus | |
octadecan-1-ol | 0.1 mM, 15% inhibition, reaction with RS-batyl alcohol and 6-methyl-5,6,7,8-tetrahydropterin | Rattus norvegicus | |
Triton X-100 | 6% loss of activity at 0.1% detergent and 59% loss of activity at 0.3% detergent | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Rattus norvegicus | |
0.011 | - |
RS-2-(1-hexadecyloxy)propan-1,2-diol | with 6-methyl-5,6,7,8-tetrahydropterin as cofactor | Rattus norvegicus | |
0.0183 | - |
2-hexadecyloxypropane-1,3-diol | with 6-methyl-5,6,7,8-tetrahydropterin as cofactor | Rattus norvegicus | |
0.0204 | - |
S-3-octadecyloxypropane-1,2-diol | with 6-methyl-5,6,7,8-tetrahydropterin as cofactor | Rattus norvegicus | |
0.0246 | - |
6R-5,6,7,8-tetrahydrobiopterin | reaction with batyl alcohol | Rattus norvegicus | |
0.0247 | - |
RS-3-octadecyloxypropane-1,2-diol | with 6-methyl-5,6,7,8-tetrahydropterin as cofactor | Rattus norvegicus | |
0.0265 | - |
RS-3-(1-hexadecyloxy)1-methoxypropan-2-ol | with 6-methyl-5,6,7,8-tetrahydropterin as cofactor | Rattus norvegicus | |
0.0313 | - |
2-octadecyloxyethan-1-ol | with 6-methyl-5,6,7,8-tetrahydropterin as cofactor | Rattus norvegicus | |
0.0397 | - |
R-3-pentadecyloxypropane-1,2-diol | with 6-methyl-5,6,7,8-tetrahydropterin as cofactor | Rattus norvegicus | |
0.0415 | - |
R-3-octadecyloxypropane-1,2-diol | with 6-methyl-5,6,7,8-tetrahydropterin as cofactor | Rattus norvegicus | |
0.1 | - |
RS-3-(1-hexadecyloxy)propan-1-ol | with 6-methyl-5,6,7,8-tetrahydropterin as cofactor | Rattus norvegicus | |
0.137 | - |
S-3-(1-hexadecyloxy)-2-hydroxypropane-1-phosphocholine | with 6-methyl-5,6,7,8-tetrahydropterin as cofactor | Rattus norvegicus | |
0.173 | - |
RS-3-(1-hexadecyloxy)-2-hydroxypropane-1-phosphocholine | with 6-methyl-5,6,7,8-tetrahydropterin as cofactor | Rattus norvegicus | |
51.3 | - |
RS-3-heptyloxypropane-1,2-diol | with 6-methyl-5,6,7,8-tetrahydropterin as cofactor | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(RS)-batyl alcohol + 6-methyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
2-(1-hexadecyloxy)propan-1,3-diol + RS-6-methyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
2-(1-octadecyloxy)ethanol + RS-(cis)-6,7-dimethyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
2-(1-octadecyloxy)ethanol + RS-6-methyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
3-(1-octadecylthio)propan-1,2-diol + RS-6-methyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
batyl alcohol + 6R-5,6,7,8-tetrahydrobiopterin + O2 | i.e. RS-3-(1-octadecyloxy)propan-1,2-doiol | Rattus norvegicus | ? | - |
? | |
batyl alcohol + RS-(cis)-6,7-dimethyl-5,6,7,8-tetrahydropterin + O2 | i.e. RS-3-(1-octadecyloxy)propan-1,2-diol | Rattus norvegicus | ? | - |
? | |
R-3-(1-octadecyloxy)propan-1,2-diol + RS-6-methyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
R-3-pentadecyloxypropan-1,2-diol + 6-methyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
RS-3-(1-heptyloxy)propan-1,2-diol + RS-6-methyl-5,6,7,8-tetrahydropterin | - |
Rattus norvegicus | ? | - |
? | |
RS-3-(1-hexadecyloxy)-1-methoxypropan-2-ol + RS-6-methyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
RS-3-(1-hexadecyloxy)-2-hydroxypropane-1-phosphocholine + RS-6-methyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
RS-3-(1-hexadecyloxy)propan-1,2-diol + RS-6-methyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
RS-3-(1-hexadecyloxy)propan-1-ol + RS-6-methyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
RS-3-(1-oleyloxy)propan-1,2-diol + RS-6-methyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
S-3-(1-hexadecyloxy)-2-hydroxypropane-1-phosphocholine + RS-6-methyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? | |
S-3-(1-octadecyloxy)propan-1,2-diol + RS-6-methyl-5,6,7,8-tetrahydropterin + O2 | - |
Rattus norvegicus | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.7 | - |
formation of glyceryl ether products | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
(6R)-5,6,7,8-tetrahydrobiopterin | - |
Rattus norvegicus | |
(RS)-6,7-dimethyl-5,6,7,8-tetrahydropterin | - |
Rattus norvegicus | |
(RS)-6-methyl-5,6,7,8-tetrahydropterin | - |
Rattus norvegicus |