Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | MICAL2 localizes in the nucleus of acute and chronic regenerating muscle fibers | Mus musculus | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q8BML1 | isoform MICAL2 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
C2C12 cell | C2C12 and satellite cells require MICAL2 for myogenic differentiation | Mus musculus | - |
muscle | MICAL2 localizes in the nucleus of acute and chronic regenerating muscle fibers | Mus musculus | - |
pluripotent stem cell | MICAL2 expression increases during myogenic differentiation of adult and pluripotent stem cells | Mus musculus | - |
satellite cell | C2C12 and satellite cells require MICAL2 for myogenic differentiation | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
Mical2 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | MICAL2 is essential for skeletal muscle homeostasis and functionality. Lack of MICAL2 results in muscle actin defects. MICAL2 upregulation shows a positive impact on skeletal and cardiac muscle commitments | Mus musculus |