Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli CodonPlus RIPL cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C118A | the mutant shows wild type activity | Homo sapiens |
C118A/C129A | the mutant shows wild type activity | Homo sapiens |
C129A | the mutant shows wild type activity | Homo sapiens |
C129A/H134A | the mutant shows 65% of wild type activity | Homo sapiens |
C304A | the mutant shows wild type activity | Homo sapiens |
C304A/C371A | the mutant shows wild type activity | Homo sapiens |
C371A | the mutant shows wild type activity | Homo sapiens |
C371A/H372A | the mutant shows wild type activity | Homo sapiens |
H113A | the mutant shows wild type activity | Homo sapiens |
H113A/C118A | the mutant shows 83% of wild type activity | Homo sapiens |
H113A/C118A/C129A/H134A | the mutant shows 69% of wild type activity | Homo sapiens |
H113A/C129A | the mutant shows wild type activity | Homo sapiens |
H134A | the mutant shows wild type activity | Homo sapiens |
H303A | the mutant shows wild type activity | Homo sapiens |
H303A/C304A | the mutant shows wild type activity | Homo sapiens |
H372A | the mutant shows wild type activity | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA-base-CH3 + 2-oxoglutarate + O2 | Homo sapiens | - |
DNA-base + formaldehyde + succinate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA-base-CH3 + 2-oxoglutarate + O2 | - |
Homo sapiens | DNA-base + formaldehyde + succinate + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ABH1 | - |
Homo sapiens |
AlkB homolog 1 | - |
Homo sapiens |