Literature summary for 1.13.12.2 extracted from

Rohles, C.; Giesselmann, G.; Kohlstedt, M.; Wittmann, C.; Becker, J.
Systems metabolic engineering of Corynebacterium glutamicum for the production of the carbon-5 platform chemicals 5-aminovalerate and glutarate (2016), Microb. Cell Fact., 15, 154 .

Search for more literature for 1.13.12.2

Cloned(Commentary)

Cloned (Comment)	Organism
gene davB, recombinant expression in Corynebacterium glutamicum strain LYS-12, coexpression with Pseudomonas putida gene davA, encoding 5-aminovaleramidase	Pseudomonas putida

Protein Variants

Protein Variants	Comment	Organism
additional information	installation of an expression system for production of 5-aminovalerate in Corynebacterium glutamicum strain LYS-12 by coexpressing gene davA, encoding 5-aminovaleramidase, and davB, encoding lysine monooxygenase, resulting in strains AVA-1-3. 5-Aminovalerate production is established. Related to the presence of endogenous genes coding for 5-aminovalerate transaminase (gabT) and glutarate semialdehyde dehydrogenase, 5-aminovalerate is partially converted to glutarate. Residual L-lysine is secreted as by-product. Putative gabT gene is deleted to enhance 5-aminovalerate production, method optimization and evaluation, overview	Pseudomonas putida

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-lysine + O2	Pseudomonas putida	-	5-aminopentanamide + CO2 + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas putida	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-lysine + O2	-	Pseudomonas putida	5-aminopentanamide + CO2 + H2O	-	?

Synonyms

Synonyms	Comment	Organism
davB	-	Pseudomonas putida
lysine monooxygenase	-	Pseudomonas putida

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Release 2023.1 (January 2023)