Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | intraarticular glucocorticoid treatment does not influence the 15-LO-1 enzyme in rheumatoid arthritis tissue | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endothelial cell | CD31+ cell, rheumatoid arthritis tissue | Homo sapiens | - |
epithelium | airway | Homo sapiens | - |
fibroblast | rheumatoid arthritis tissue | Homo sapiens | - |
macrophage | rheumatoid arthritis tissue | Homo sapiens | - |
additional information | present in SF cells of rheumatoid arthritis tissue, absent in CD3+ T cells or in CD20+ B cells of rheumatoid arthritis tissue | Homo sapiens | - |
rheumatoid arthritis synovial tissue | higher expression of 15-LO-1 compared with ostheoarthritis synovial tissue | Homo sapiens | - |
synovial cell | low expression of 15-LO-1 in ostheoarthritis synovial tissue | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
arachidonate + O2 | - |
Homo sapiens | (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
15-lipoxygenase | - |
Homo sapiens |
15-LO-1 | - |
Homo sapiens |