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Literature summary for 1.13.11.27 extracted from

  • Dreesen, R.; Capt, A.; Oberdoerfer, R.; Coats, I.; Pallett, K.E.
    Characterization and safety evaluation of HPPD W336, a modified 4-hydroxyphenylpyruvate dioxygenase protein, and the impact of its expression on plant metabolism in herbicide-tolerant MST-FGO72-2 soybean (2018), Regul. Toxicol. Pharmacol., 97, 170-185 .
    View publication on PubMed

Application

Application Comment Organism
agriculture 4-hydroxyphenylpyruvate dioxygenase modified at position 336 (HPPD W336) is expressed in MST-FGO72-2 soybean to confer tolerance to 4-benzoyl isoxazole and triketone type of herbicides. No relevant sequence homologies are found with known allergens or toxins, and the absence of hemolytic activity of HPPD W336 is demonstrated in vitro. HPPD W336 degrades rapidly in simulated gastric fluid. Expression of HPPD W336 does not change aromatic amino acid, homogentisate and tocochromanol levels in soybean seed Pseudomonas fluorescens

Organism

Organism UniProt Comment Textmining
Pseudomonas fluorescens
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Pseudomonas fluorescens A32
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