Literature summary for 1.13.11.27 extracted from

Wang, H.; Liu, B.; Lei, P.; Zhu, J.; Chen, L.; He, Q.; He, J.
Improving the herbicide resistance of 4-hydroxyphenylpyruvate dioxygenase SpHPPD by directed evolution (2022), Enzyme Microb. Technol., 154, 109964 .

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Protein Variants

Protein Variants	Comment	Organism
E322R	mutant shows improved resistance to topramezone, with about 98% of wild-type activity, and displays increased resistance to mesotrione	Sphingobium sp. TPM-19
K249R	mutant shows improved resistance to topramezone, with about 98% of wild-type activity, and displays increased resistance to mesotrione and DKN, i.e. the active ingredient of isoxaflutole	Sphingobium sp. TPM-19

Inhibitors

Inhibitors	Comment	Organism	Structure
topramezone	-	Sphingobium sp. TPM-19

Organism

Organism	UniProt	Comment	Textmining
Sphingobium sp. TPM-19	-	-	-

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Release 2023.1 (January 2023)