Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(+)-gossypol | potent inhibitor | Homo sapiens | |
(+)-gossypol | potent inhibitor | Rattus norvegicus | |
(-)-gossypol | potent inhibitor | Homo sapiens | |
(-)-gossypol | potent inhibitor | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
microsome | - |
Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Homo sapiens | - |
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pregnenolone + NAD+ | - |
Homo sapiens | progesterone + NADH + H+ | - |
? | |
pregnenolone + NAD+ | - |
Rattus norvegicus | progesterone + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3beta-HSD | - |
Homo sapiens |
3beta-HSD | - |
Rattus norvegicus |
3beta-hydroxysteroid dehydrogenase | - |
Homo sapiens |
3beta-hydroxysteroid dehydrogenase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens | |
NAD+ | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00019 | - |
in PBS buffer, pH 7.2 | Rattus norvegicus | (+)-gossypol | |
0.00023 | - |
in PBS buffer, pH 7.2 | Rattus norvegicus | (-)-gossypol | |
0.00277 | - |
in PBS buffer, pH 7.2 | Homo sapiens | (-)-gossypol | |
0.00445 | - |
in PBS buffer, pH 7.2 | Homo sapiens | (+)-gossypol |