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UDP-alpha-D-galactose + 4-beta-D-galactosyl-O-beta-D-xylosyl-[protein]
UDP + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-[protein]
-
-
-
?
UDP-alpha-D-galactose + 4-methylumbelliferyl-beta-D-xylopyranoside
UDP + ?
-
-
-
?
UDP-galactose + 4-beta-D-galactosyl-O-beta-D-xylose
UDP + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylose
UDP-galactose + 4-beta-D-galactosyl-O-beta-D-xylosylprotein
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-xylosylprotein
-
involved in biosynthesis of chondroitin sulfate
-
-
?
UDP-galactose + beta-D-galactosyl-1,3-beta-galactosyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,3-beta-galactosyl-O-naphthalenemethanol
UDP-galactose + beta-D-galactosyl-1,3-N-acetyl-alpha-D-glucosaminyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-glucosaminyl-O-naphthalenemethanol
UDP-galactose + beta-D-galactosyl-1,3-N-acetyl-beta-D-glucosaminyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,3-N-acetyl-beta-D-glucosaminyl-O-naphthalenemethanol
-
-
-
?
UDP-galactose + beta-D-galactosyl-1,4-beta-D-xylosyl-O-benzyl
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-xylosyl-O-benzyl
UDP-galactose + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-O-naphthalenemethanol
UDP-galactose + beta-D-galactosyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-O-naphthalenemethanol
UDP-galactose + beta-galactosides
?
-
e.g. phenyl or pyridine 3-O-beta-galactosides, poor substrate: pyridine 2-S-beta-thiogalactoside, no substrate: D-galactose
-
-
?
UDP-galactose + galactosyl-xylosylserine
UDP + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylserine
-
-
-
?
UDP-galactose + Galalpha-p-nitrophenol
?
Drosophila sp. (in: flies)
-
-
-
-
?
UDP-galactose + Galbeta-p-nitrophenol
?
Drosophila sp. (in: flies)
-
-
-
-
?
UDP-galactose + Galbeta1,4Xyl-p-methoxyphenol
?
Drosophila sp. (in: flies)
-
-
-
-
?
UDP-galactose + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-O-naphthalenemethanol
-
-
-
?
UDP-galactose + pyridine 3-O-beta-D-galactoside
UDP + ?
-
-
-
-
?
additional information
?
-
UDP-galactose + 4-beta-D-galactosyl-O-beta-D-xylose
UDP + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylose
-
-
-
?
UDP-galactose + 4-beta-D-galactosyl-O-beta-D-xylose
UDP + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylose
-
-
-
-
?
UDP-galactose + beta-D-galactosyl-1,3-beta-galactosyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,3-beta-galactosyl-O-naphthalenemethanol
-
-
-
?
UDP-galactose + beta-D-galactosyl-1,3-beta-galactosyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,3-beta-galactosyl-O-naphthalenemethanol
-
-
-
-
?
UDP-galactose + beta-D-galactosyl-1,3-beta-galactosyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,3-beta-galactosyl-O-naphthalenemethanol
-
-
-
-
?
UDP-galactose + beta-D-galactosyl-1,3-N-acetyl-alpha-D-glucosaminyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-glucosaminyl-O-naphthalenemethanol
-
-
-
-
?
UDP-galactose + beta-D-galactosyl-1,3-N-acetyl-alpha-D-glucosaminyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-glucosaminyl-O-naphthalenemethanol
-
-
-
-
?
UDP-galactose + beta-D-galactosyl-1,4-beta-D-xylosyl-O-benzyl
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-xylosyl-O-benzyl
-
-
-
?
UDP-galactose + beta-D-galactosyl-1,4-beta-D-xylosyl-O-benzyl
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-xylosyl-O-benzyl
-
-
-
-
?
UDP-galactose + beta-D-galactosyl-1,4-beta-D-xylosyl-O-benzyl
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-xylosyl-O-benzyl
-
-
-
-
?
UDP-galactose + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-O-naphthalenemethanol
-
-
-
?
UDP-galactose + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-O-naphthalenemethanol
-
-
-
-
?
UDP-galactose + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-O-naphthalenemethanol
-
-
-
-
?
UDP-galactose + beta-D-galactosyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-O-naphthalenemethanol
-
-
-
-
?
UDP-galactose + beta-D-galactosyl-O-naphthalenemethanol
UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-O-naphthalenemethanol
-
-
-
-
?
additional information
?
-
Drosophila sp. (in: flies)
-
dbeta3GalTII is involved in heparan sulfate synthesis for wing and eye development. dbeta3GalTII contributes to heparan sulfate proteoglycan synthesis in vitro and in vivo and also modulates Wingless distribution
-
-
?
additional information
?
-
-
modeling of 3-D structures of human b3GalT I, II, IV, V, and VI using fold-recognition and comparative modeling methods. Prediction of residues that constitute the UDP-Gal binding site. The models are able to qualitatively rationalize data from the site-directed mutagenesis experiments reported in the literature
-
-
?
additional information
?
-
modeling of 3-D structures of human b3GalT I, II, IV, V, and VI using fold-recognition and comparative modeling methods. Prediction of residues that constitute the UDP-Gal binding site. The models are able to qualitatively rationalize data from the site-directed mutagenesis experiments reported in the literature
-
-
?
additional information
?
-
modeling of 3-D structures of human b3GalT I, II, IV, V, and VI using fold-recognition and comparative modeling methods. Prediction of residues that constitute the UDP-Gal binding site. The models are able to qualitatively rationalize data from the site-directed mutagenesis experiments reported in the literature
-
-
?
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2660
pmol/h/ml medium, beta-D-galactosyl-1,4-beta-xylosyl-O-benzyl as substrate
3
pmol/h/ml medium, beta-D-galactosyl-1,3-beta-D-galactosyl-O-naphthalenemethanol as substrate
1
pmol/h/ml medium, beta-D-galactosyl-1,3-N-acetyl-beta-D-glucosaminyl-O-naphthalenemethanol as substrate
1
-
pmol/h/ml medium, beta-D-galactosyl-1,3-beta-D-galactosyl-O-naphthalenemethanol as substrate
1
-
pmol/h/ml medium, beta-D-galactosyl-1,3-beta-D-galactosyl-O-naphthalenemethanol as substrate
18
-
pmol/h/ml medium, beta-D-galactosyl-O-naphthalenemethanol as substrate
18
-
pmol/h/ml medium, beta-D-galactosyl-O-naphthalenemethanol as substrate
4
-
pmol/h/ml medium, beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-O-naphthalenemethanol as substrate
4
-
pmol/h/ml medium, beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-O-naphthalenemethanol as substrate
6
pmol/h/ml medium, N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-O-naphthalenemethanol as substrate
6
-
pmol/h/ml medium, beta-D-galactosyl-1,3-N-acetyl-alpha-D-glucosaminyl-O-naphthalenemethanol as substrate
6
-
pmol/h/ml medium, beta-D-galactosyl-1,3-N-acetyl-alpha-D-glucosaminyl-O-naphthalenemethanol as substrate
84
-
pmol/h/ml medium, beta-D-galactosyl-1,4-beta-xylosyl-O-benzyl as substrate
84
-
pmol/h/ml medium, beta-D-galactosyl-1,4-beta-xylosyl-O-benzyl as substrate
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B3GT6_HUMAN
329
1
37138
Swiss-Prot
Secretory Pathway (Reliability: 3)
B3GT6_MOUSE
325
1
37021
Swiss-Prot
Secretory Pathway (Reliability: 4)
PVG3_SCHPO
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
378
1
43834
Swiss-Prot
Secretory Pathway (Reliability: 1)
SQV2_CAEEL
330
1
37973
Swiss-Prot
Secretory Pathway (Reliability: 1)
G7IP42_MEDTR
689
1
78025
TrEMBL
Secretory Pathway (Reliability: 5)
A0A2G9GCR7_9LAMI
677
1
77103
TrEMBL
Secretory Pathway (Reliability: 5)
B9S8X5_RICCO
631
1
71156
TrEMBL
Secretory Pathway (Reliability: 5)
A0A2G9HCI0_9LAMI
662
1
75668
TrEMBL
Secretory Pathway (Reliability: 5)
A0A5B8G4R3_DENOF
678
1
77251
TrEMBL
Mitochondrion (Reliability: 5)
A0A2P6QZE3_ROSCH
652
1
73683
TrEMBL
Mitochondrion (Reliability: 2)
A0A8M1NAH5_DANRE
335
1
38592
TrEMBL
Secretory Pathway (Reliability: 1)
B9SYI3_RICCO
683
1
77951
TrEMBL
Mitochondrion (Reliability: 3)
A0A2G9I0I0_9LAMI
627
1
70613
TrEMBL
Secretory Pathway (Reliability: 3)
A0A5B8G675_DENOF
678
1
77038
TrEMBL
Mitochondrion (Reliability: 3)
B9S2F1_RICCO
638
0
73009
TrEMBL
Secretory Pathway (Reliability: 3)
A0A2P6Q5T4_ROSCH
678
1
77499
TrEMBL
Mitochondrion (Reliability: 5)
A0A072URG8_MEDTR
642
1
72354
TrEMBL
Secretory Pathway (Reliability: 5)
G7KFC0_MEDTR
639
1
71946
TrEMBL
Secretory Pathway (Reliability: 2)
A0A2P6P2B2_ROSCH
651
1
73885
TrEMBL
Mitochondrion (Reliability: 2)
A0A2G9GBK5_9LAMI
665
1
75329
TrEMBL
Mitochondrion (Reliability: 4)
G7LDT0_MEDTR
652
1
75008
TrEMBL
Secretory Pathway (Reliability: 4)
B9R916_RICCO
670
1
76293
TrEMBL
Mitochondrion (Reliability: 4)
A0A2P6R4A7_ROSCH
660
1
76055
TrEMBL
Mitochondrion (Reliability: 5)
A0A2P6R2X1_ROSCH
655
1
73303
TrEMBL
other Location (Reliability: 2)
G7K899_MEDTR
643
1
73496
TrEMBL
Secretory Pathway (Reliability: 2)
A0A072URC6_MEDTR
616
1
70301
TrEMBL
Mitochondrion (Reliability: 4)
B3GT1_HUMAN
326
1
37993
Swiss-Prot
other Location (Reliability: 3)
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Schwartz, N.B.; Rodn, L.
Biosynthesis of chondroitin sulfate. Solubilization of chondroitin sulfate glycosyltransferases and partial purification of uridine diphosphate-D-galactose:D-xylose galactosyltrans
J. Biol. Chem.
250
5200-5207
1975
Gallus gallus
brenda
Robinson, J.A.; Robinson, H.C.
Initiation of chondroitin sulphate synthesis by beta-D-galactosides. Substrates for galactosyltransferase II
Biochem. J.
227
805-814
1985
Gallus gallus
brenda
Hwang, H.Y.; Olson, S.K.; Brown, J.R.; Esko, J.D.; Horvitz, H.R.
The Caenorhabditis elegans genes sqv-2 and sqv-6, which are required for vulval morphogenesis, encode glycosaminoglycan galactosyltransferase II and xylosyltransferase
J. Biol. Chem.
278
11735-11738
2003
Caenorhabditis elegans (Q9N491)
brenda
Sun, S.; Schilling, B.; Tarantino, L.; Tullius, M.V.; Gibson, B.W.; Munson, R.S., Jr.
Cloning and characterization of the lipooligosaccharide galactosyltransferase II gene of Haemophilus ducreyi
J. Bacteriol.
182
2292-2298
2000
[Haemophilus] ducreyi
brenda
Nakamura, N.; Yamakawa, N.; Sato, T.; Tojo, H.; Tachi, C.; Furukawa, K.
Differential gene expression of beta-1,4-galactosyltransferases I, II and V during mouse brain development
J. Neurochem.
76
29-38
2001
Mus musculus
brenda
Bai, X.; Zhou, D.; Brown, J.R.; Crawford, B.E.; Hennet, T.; Esko, J.D.
Biosynthesis of the linkage region of glycosaminoglycans. Cloning and activity of galactosyltransferase II, the sixth member of the beta1,3-galactosyltransferase family (beta3GalT6)
J. Biol. Chem.
276
48189-48195
2001
Homo sapiens, Mus musculus
brenda
Ueyama, M.; Takemae, H.; Ohmae, Y.; Yoshida, H.; Toyoda, H.; Ueda, R.; Nishihara, S.
Functional analysis of proteoglycan galactosyltransferase II RNA interference mutant flies
J. Biol. Chem.
283
6076-6084
2008
Drosophila sp. (in: flies)
brenda
Patel, R.Y.; Balaji, P.V.
Fold-recognition and comparative modeling of human beta3GalTI, II, IV, V and VI and beta 3GalNAcT I: Prediction of residues conferring acceptor substrate specificity
J. Mol. Graph. Model.
26
255-268
2007
Homo sapiens, Homo sapiens (Q96L58), Homo sapiens (Q9Y5Z6)
brenda
Tew, S.R.; Pothacharoen, P.; Katopodi, T.; Hardingham, T.E.
SOX9 transduction increases chondroitin sulfate synthesis in cultured human articular chondrocytes without altering glycosyltransferase and sulfotransferase transcription
Biochem. J.
414
231-236
2008
Homo sapiens
brenda
Malfait,F.; Kariminejad, A.; Van Damme,T.; Gauche, C.; Syx, D.; Merhi-Soussi, F.; Gulberti, S.; Symoens, S.; Vanhauwaert, S.; Willaert, A.; Bozorgmehr, B.; Kariminejad, M.H.; Ebrahimiadib, N.; Hausser, I.; Huysseune, A.; Fournel-Gigleux, S.; De Paepe, A.
Defective initiation of glycosaminoglycan synthesis due to B3GALT6 mutations causes a pleiotropic Ehlers-Danlos-Syndrome-like connective tissue disorder
Am. J. Hum. Genet.
92
935-945
2013
Homo sapiens (Q96L58)
brenda