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Information on EC 2.1.1.384 - [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]—tetrahydromethanopterin methyltransferase

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EC Tree
IUBMB Comments
The enzyme has been characterized from several archaeal species. In the methanogenic archaeon Methermicoccus shengliensis the enzyme participates in methanogenesis from methoxylated aromatic compounds, while in the non-methanogenic Archaeoglobus fulgidus it participates in methoxydotrophic growth. The enzyme catalyses the transfer of a methyl group bound to the cobalt cofactor of a dedicated corrinoid protein (MtoC) to tetrahydromethanopterin or tetrahydrosarcinapterin. cf. EC 2.1.1.385, [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]---tetrahydrofolate methyltransferase.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
a [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]
+
=
N5-methyltetrahydromethanopterin
+
a [Co(I) methoxylated-aromatic-compound-specific corrinoid protein]
Synonyms
AF_0009, mtoA, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein] + tetrahydromethanopterin = N5-methyltetrahydromethanopterin + a [Co(I) methoxylated-aromatic-compound-specific corrinoid protein]
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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