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Information on EC 2.1.1.377 - [methyl-Co(III) glycine betaine-specific corrinoid protein]-coenzyme M methyltransferase

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EC Tree
IUBMB Comments
The enzyme, which is involved in methanogenesis from glycine betaine, catalyses the transfer of a methyl group bound to the cobalt cofactor of glycine betaine-specific corrinoid protein to coenzyme M, forming the substrate for EC 2.8.4.1, coenzyme-B sulfoethylthiotransferase, which catalyses the final step in methanogenesis. The enzyme from the methanogenic archaeon Methanolobus vulcani B1d can also catalyse the activity of EC 2.1.1.246, [methyl-Co(III) methanol-specific corrinoid protein]---coenzyme M methyltransferase.
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The expected taxonomic range for this enzyme is: Methanolobus vulcani
Reaction Schemes
a [methyl-Co(III) glycine betaine-specific corrinoid protein]
+
=
+
a [Co(I) glycine betaine-specific corrinoid protein]
Synonyms
mv10360, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a [methyl-Co(III) glycine betaine-specific corrinoid protein] + CoM = methyl-CoM + a [Co(I) glycine betaine-specific corrinoid protein]
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PATHWAY SOURCE
PATHWAYS
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