Disease on EC 2.1.1.28 - phenylethanolamine N-methyltransferase
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Acute Kidney Injury
Phenylethanolamine N-methyltransferase gene polymorphisms and adverse outcomes in acute kidney injury.
Alzheimer Disease
Degenerative changes in epinephrine tonic vasomotor neurons in Alzheimer's disease.
Alzheimer Disease
Phenylethanolamine N-methyltransferase (PNMT) gene and early-onset Alzheimer disease.
Alzheimer Disease
Phenylethanolamine N-methyltransferase activity is decreased in Alzheimer's disease brains.
Anemia, Sickle Cell
Phenylethanolamine N-methyltransferase gene polymorphisms associate with crisis pain in sickle cell disease patients.
Asthma
?2-Adrenoceptor agonists are required for development of the asthma phenotype in a murine model.
Asthma
Epistasis between phenylethanolamine N-methyltransferase and ?2-adrenergic receptor influences extracellular epinephrine level and associates with the susceptibility to allergic asthma.
Bradycardia
The effects of PNMT inhibitors upon cardiovascular changes induced by hemorrhage in the rat.
Breast Neoplasms
Gene expression profiling detects gene amplification and differentiates tumor types in breast cancer.
Cardiomyopathies
Increased gene expression of catecholamine-synthesizing enzymes in adrenal glands contributes to high circulating catecholamines in pigs with tachycardia-induced cardiomyopathy.
Cholera
Adrenergic innervation of forebrain neurons that project to the paraventricular thalamic nucleus in the rat.
Cholera
Quantitative analysis of spinally projecting adrenaline-synthesising neurons of C1, C2 and C3 groups in rat medulla oblongata.
Essential Hypertension
Phenylethanolamine N-Methyltransferase Gene Promoter Haplotypes and Risk of Essential Hypertension.
Genetic Diseases, Inborn
Tyrosine hydroxylase (TH), its cofactor tetrahydrobiopterin (BH4), other catecholamine-related enzymes, and their human genes in relation to the drug and gene therapies of Parkinson's disease (PD): historical overview and future prospects.
Herpes Zoster
Origin of cocaine- and amphetamine-regulated transcript (CART)-immunoreactive innervation of the hypothalamic paraventricular nucleus.
Hyperalgesia
The Adrenal Medulla Modulates Mechanical Allodynia in a Rat Model of Neuropathic Pain.
Hypertension
Catecholamine-stimulated cyclic AMP formation in phenylethanolamine N-methyltransferase containing brain stem nuclei of normal rats and of rats with spontaneous genetic hypertension.
Hypertension
Evidence for a sodium-induced activation of central neurogenic mechanisms in one-kidney, one-clip renal hypertensive rats.
Hypertension
Glucocorticoid hypertension and nonadrenal phenylethanolamine N-methyltransferase.
Hypertension
Investigation of the phenylethanolamine N-methyltransferase gene as a candidate gene for hypertension.
Hypertension
Normotensive incidentally discovered pheochromocytomas display specific biochemical, cellular and molecular characteristics.
Hypertension
Phenylethanolamine N-methyltransferase gene expression in PC12 cells exposed to intermittent hypoxia.
Hypertension
Structure-Based Drug Design of Bisubstrate Inhibitors of Phenylethanolamine N-Methyltransferase Possessing Low Nanomolar Affinity at Both Substrate Binding Domains1.
Hypertension, Renovascular
Catecholamine synthesizing enzymes in brain stem and hypothalamus during the development of renovascular hypertension.
Hypoglycemia
Antecedent hypoglycemia, catecholamine depletion, and subsequent sympathetic neural responses.
Hypoglycemia
Effects of insulin treatment without and with recurrent hypoglycemia on hypoglycemic counterregulation and adrenal catecholamine-synthesizing enzymes in diabetic rats.
Lichen Planus
The specificity and cellular origin of phenylethanolamine N-methyltransferase (PNMT)-like immunoreactivity in psoriatic skin.
Lordosis
Inhibition of guinea pig lordosis behavior by the phenylethanolamine N-methyltransferase (PNMT) inhibitor SKF-64139: mediation by alpha noradrenergic receptors.
Medulloblastoma
Regulation of PNMT gene promoter constructs transfected into the TE 671 human medulloblastoma cell line.
Multiple Endocrine Neoplasia
Pheochromocytomas in von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2 display distinct biochemical and clinical phenotypes.
Multiple Endocrine Neoplasia
Transcriptional regulation of phenylethanolamine N-methyltransferase in pheochromocytomas from patients with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2.
Multiple Endocrine Neoplasia Type 2a
Pheochromocytomas in von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2 display distinct biochemical and clinical phenotypes.
Multiple Endocrine Neoplasia Type 2a
Transcriptional regulation of phenylethanolamine N-methyltransferase in pheochromocytomas from patients with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2.
Multiple Sclerosis
Association between the phenylethanolamine N-methyltransferase gene and multiple sclerosis.
Neoplasms
A developmental model of neuroblastoma: differentiating stroma-poor tumors' progress along an extra-adrenal chromaffin lineage.
Neoplasms
Cushing Syndrome Due to ACTH-Secreting Pheochromocytoma, Aggravated by Glucocorticoid-Driven Positive-Feedback Loop.
Neoplasms
Hypoxia-inducible Factor 2?: A Key Player in Tumorigenesis and Metastasis of Pheochromocytoma and Paraganglioma?
Neoplasms
Pheochromocytomas in von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2 display distinct biochemical and clinical phenotypes.
Neoplasms
Studies of a transplantable rat pheochromocytoma: biochemical characterization and catecholamine secretion.
Neoplasms
Transcriptional regulation of phenylethanolamine N-methyltransferase in pheochromocytomas from patients with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2.
Neoplasms
Transgenic mice express the human phenylethanolamine N-methyltransferase gene in adrenal medulla and retina.
Pancreatic Neoplasms
Expression profiles of pancreatic cancer cell lines infected with antisense K-ras-expressing adenoviral vector.
Papilloma
Characterization of recombinant bovine phenylethanolamine N-methyltransferase expressed in a mouse C127 cell line.
Parkinson Disease
Loss of C1 and C3 epinephrine-synthesizing neurons in the medulla oblongata in Parkinson's disease.
Parkinson Disease
Phenylethanolamine N-methyltransferase has beta-carboline 2N-methyltransferase activity: hypothetical relevance to Parkinson's disease.
Parkinson Disease
Tyrosine hydroxylase (TH), its cofactor tetrahydrobiopterin (BH4), other catecholamine-related enzymes, and their human genes in relation to the drug and gene therapies of Parkinson's disease (PD): historical overview and future prospects.
Parkinsonian Disorders
Phenylethanolamine N-methyltransferase and other enzymes of catecholamine metabolism in human brain.
Pheochromocytoma
Deficiency of Phenylethanolamine N-Methyltransferase in Norepinephrine-Producing Pheochromocytoma.
Pheochromocytoma
Immunohistochemical localization of catecholamine-synthesizing enzymes in human pheochromocytomas.
Pheochromocytoma
Normotensive incidentally discovered pheochromocytomas display specific biochemical, cellular and molecular characteristics.
Pheochromocytoma
Pheochromocytomas in von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2 display distinct biochemical and clinical phenotypes.
Pheochromocytoma
Transcriptional regulation of phenylethanolamine N-methyltransferase in pheochromocytomas from patients with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2.
Psoriasis
Phenylethanolamine N-methyltransferase-like immunoreactivity in psoriasis. An immunohistochemical study on catecholamine synthesizing enzymes and neuropeptides of the skin.
Reperfusion Injury
Activation of Different Neuronal Phenotypes in the Rat Brain Induced by Liver Ischemia-Reperfusion Injury: Dual Fos/Neuropeptide Immunohistochemistry.
von Hippel-Lindau Disease
Transcriptional regulation of phenylethanolamine N-methyltransferase in pheochromocytomas from patients with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2.
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