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Information on EC 1.14.14.147 - 22alpha-hydroxysteroid 23-monooxygenase

for references in articles please use BRENDA:EC1.14.14.147
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EC Tree
IUBMB Comments
A cytochrome P-450 (heme-thiolate) protein involved in brassinosteroid biosynthesis in plants. The enzyme has a relaxed substrate specificity, and C-23 hydroxylation can occur at different stages in the pathway. In Arabidopsis thaliana two isozymes, encoded by the CYP90C1 and CYP90D1 genes, have redundant activities.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
cyp90d1, cyp90c1, cyp90c1/rotundifolia3, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(22S,24R)-22-hydroxy-5alpha-ergostan-3-one + [reduced NADPH-hemoprotein reductase] + O2 = 3-dehydro-6-deoxoteasterone + [oxidized NADPH-hemoprotein reductase] + H2O
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(2)
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3-epi-6-deoxocathasterone + [reduced NADPH-hemoprotein reductase] + O2 = 6-deoxotyphasterol + [oxidized NADPH-hemoprotein reductase] + H2O
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(1)
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