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Information on EC 1.14.13.240 - 2-polyprenylphenol 6-hydroxylase

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IUBMB Comments
Contains FAD. The enzyme from the bacterium Escherichia coli (UbiI) catalyses the first hydroxylation during the aerobic biosynthesis of ubiquinone. The enzyme from the bacterium Neisseria meningitidis (UbiM) can also catalyse the two additional hydroxylations that occur in the pathway (cf. EC 1.14.99.60, 3-demethoxyubiquinol 3-hydroxylase).
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
2-octaprenylphenol hydroxylase, HMPREF0602_0026, ubiI, ubiM, visC, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-(all-trans-polyprenyl)phenol + NADPH + H+ + O2 = 3-(all-trans-polyprenyl)benzene-1,2-diol + NADP+ + H2O
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