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Information on EC 1.14.13.218 - 5-methylphenazine-1-carboxylate 1-monooxygenase

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IUBMB Comments
The enzyme, characterized from the bacterium Pseudomonas aeruginosa, is involved in the biosynthesis of pyocyanin, a toxin produced and secreted by the organism. It can also act on phenazine-1-carboxylate, converting it into phenazin-1-ol.
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The enzyme appears in viruses and cellular organisms
Synonyms
PA4217, phzS, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
5-methylphenazine-1-carboxylate + NADH + O2 = pyocyanin + NAD+ + CO2 + H2O
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